Chemotherapy induced nausea and vomiting (CINV) is a distressing symptom for cancer patients. Nausea is used to describe the sensation of feeling sick, whereas vomiting describes being sick.
CINV is experienced by up to 75% of all cancer patients. Management is important to improve nutritional status of patients and quality of life.
CINV can be classified according to time of onset:
Chemotherapy Induced Nausea and Vomiting Treatment
Serotonin receptor antagonists (e.g. ondansetron, granisetron, palonosetron) form the basis of treatment for CINV. Dexamethasone and aprepitant are other effective anti-sickness medications for CINV. Other classes of anti-sickness medications are commonly used in combination with the above drugs.
Medicinal cannabis can be considered when first line therapies have not achieved adequate symptom control.