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Chemotherapy Induced Nausea and Vomiting

Chemotherapy induced nausea and vomiting (CINV) is a distressing symptom for cancer patients. Nausea is used to describe the sensation of feeling sick, whereas vomiting describes being sick.

CINV is experienced by up to 75% of all cancer patients. Management is important to improve nutritional status of patients and quality of life.

Chemotherapy Induced Nausea and Vomiting Treatment

Serotonin receptor antagonists (e.g. ondansetron, granisetron, palonosetron) form the basis of treatment for CINV. Dexamethasone and aprepitant are other effective anti-sickness medications for CINV. Other classes of anti-sickness medications are commonly used in combination with the above drugs.

Medicinal cannabis can be considered when first line therapies have not achieved adequate symptom control.