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Crohn’s Disease

Crohn’s disease is an autoimmune condition caused by the body’s immune system attacking itself. This causes patches of inflammation in the gut wall, affecting any part of the gut.

145 in 100,000 adults in the UK are affected by Crohn’s disease.

Crohn’s Disease Treatment

Treatment for Crohn’s disease is separated into two components. The first aim is to treat active symptoms (flare-up) and then once a flare-up is settled to maintain remission.

Treatment for Crohn’s disease is managed in specialist settings.

Flare-ups are typically treated with a short course of corticosteroids with other immunosuppressant medications (e.g. azathioprine, 6-mercaptopurine) depending on severity.

Remission is maintained using a stepwise approach starting with select immunosuppressants (e.g. azathioprine, 6-mercpatopurine) and adding in second line therapies (e.g. methotrexate) as required.

Some patients may require treatment with special medications made from antibodies or surgery.

Medicinal cannabis can be considered when first and second line therapies have not achieved adequate benefit in active Crohn’s disease or disease that is in remission.